Higher serum aldosterone levels among patients with chronic kidney disease (CKD) are independently associated with an increased risk for CKD progression and end-stage kidney disease (ESKD) regardless ...

Boston, MA - A new analysis of participants in the Framingham Offspring study has shown that aldosterone levels at the high end of normal appear to predispose people to hypertension [1]. Reporting ...

Please provide your email address to receive an email when new articles are posted on . Dysregulated aldosterone production, sometimes driven by obesity, can cause hypertension. Targeted therapies ...

Aldosterone is a hormone that causes salt retention, which raises blood pressure. Some people have abnormally high aldosterone levels, but it's difficult to accurately assess aldosterone levels ...

Please provide your email address to receive an email when new articles are posted on . Half of participants experienced a clinically meaningful decrease in albuminuria after taking BI 690517. Of ...

Lorundrostat, a novel therapy which blocks the production of aldosterone from the adrenal glands, demonstrated clinically meaningful and sustained reductions in blood pressure in 1,083 patients with ...

Aldosterone is a hormone that helps regulate sodium and potassium levels in the blood. Hyperaldosteronism and hypoaldosteronism are conditions involving abnormal aldosterone levels. The adrenal glands ...

Hyperaldosteronism is when one or both adrenal glands release too much of the hormone aldosterone. High blood pressure can result, which could lead to atrial fibrillation, heart attack, or stroke.

As the cells differentiated, they expressed even higher levels of genes involved in aldosterone synthesis and became increasingly active. "The identification of two distinct cell fates in APAs ...