Scientists see the first steps of DNA unwinding

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...
Baylor College of Medicine

First step to untangle DNA: supercoiled DNA captures gyrase like a lasso ropes cattle

Picture in your mind a traditional “landline” telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...
The Scientist

NEB Offers New Route to Amplify DNA Without Labor-Intensive Purification Steps

New England Biolabs (NEB) just announced its new Q5® Blood Direct 2X Master Mix. This latest DNA polymerase master mix amplifies a wide variety of genetic targets directly from whole or dried blood — ...
News Medical

RNA steps up to protect the genome from DNA knots

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...