Three Husker students under the mentorship of Luwen Zhang, a leading University of Nebraska-Lincoln virologist, have achieved ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

A study from St. Jude Children’s Research Hospital reveals that the protein VDAC2 acts as a “signal jammer” in tumors, ...

Interferon regulatory factor 3 (IRF3) is a key transcription factor in the type I interferon signaling. Its activation must be tightly controlled to efficiently activate innate immunity while ...

Malle says that their interferon levels may be “high enough to provide ... that he likens to artificial USP18—can help smooth out how the innate immune system’s brakes are applied in DS cells and ...

The interferon signals the body’s immune defences which ... “This new discovery suggests that genes that control pigment in hair and skin also work to control the innate immune system. These results ...

St. Jude researchers identified a protein, voltage-dependent anion channel 2 (VDAC2), that tumors use as a “signal jammer” to prevent cancer cell death and evade the immune system’s functioning.