Left ventricular hypertrophy (LVH) is an abnormal thickening ... electrical activity takes longer to traverse throughout the whole heart, thus the duration of the QRS complex may be widened.

Chronic heart failure occurs when either the left ... Hypertension may cause left ventricular hypertrophy (LVH) and impaired relaxation. Over time, this condition progresses, resulting in higher ...

Since many of the observed benefits of PDE5 inhibition with regard to left ventricular hypertrophy ... relevant to the pathophysiology heart failure in patients with preserved ejection fraction ...

The theoretical benefits of ACE inhibitors specifically in HFPEF rest on the basis that angiotensin II contributes to left ventricular myocardial hypertrophy and fibrosis, impairs left ventricular ...

The FDA has accepted for Priority Review the sNDA for finerenone for heart failure with mildly reduced or preserved ejection fraction.

In the setting of many human diseases such as heart failure and pulmonary hypertension, this means that right ventricular (RV ... right heart Aging imparts known changes to the left heart- including ...

The Medscape team is back in Chicago for the much-anticipated ACC 2025 conference,  March 29-31, bringing an array of ...

You have full access to this article via your institution. Figure 1: a, Shift in calmodulin-associated CnA isoforms in the failing human left ventricle. Of the three calcineurin A isoforms (α, β ...

Inter-atrial shunt device therapy has shown mixed results in clinical trials, with clinical 'non-responders' typically showing features of more advanced heart failure. We aimed to analyse the ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Sirolimus, the active ingredient in Felycin-CA1, at a higher dose is used as an immunosuppressant in human patients receiving ...