A team of University of Kentucky Markey Cancer Center researchers has found the mechanism that grants prostate cancer ...

Dual checkpoint inhibitors led to longer overall survival in patients with high-risk endometrial cancer who displayed ...

Overexpression of ROR2, a noncanonical wnt5A signaling receptor ... About Evalstotug Evalstotug, is a CAB anti-CTLA-4 antibody that is being developed as an immuno-oncology agent with the goal ...

BioAtla is extending its runway beyond key clinical readouts in 1H 2026 by restructuring and realigning resources, which includes a workforce reduction of over 30%. The Company estimates that it will ...

CAB-EpCAM x CAB-CD3 (BA3182) Phase 1 dose-escalation study continues with data readout expected mid-2025; Dose expansion data readout anticipated 1H 2026 Mecbotamab ...

Channel 4's online TV service - now renamed Channel 4 Streaming but it's shortened to C4 – allows you to catch-up on programmes, stream live channels and dip into the archives to watch older shows, ...

The Witcher 4 has now been officially revealed, with a new trailer confirming that the game will focus on Ciri as the main protagonist. This latest look does give us an idea as to the overall ...

When is The Witcher 4 release date? CD Projekt Red initially confirmed the existence of a new game in The Witcher series via a press release in March 2022 and a title update in October 2022.

Corvus is collaborating with the Kidney Cancer Research Consortium (KCRC) in a Phase 1b/2 clinical trial evaluating ciforadenant as a potential first line therapy for metastatic renal cell cancer (RCC ...

In the tumor microenvironment, this process alters immune cell function by modifying metabolic substrates and signaling pathways (18 ... lactate in sustaining T-cell exhaustion via the PD-1/CTLA-4 ...

By influencing various signaling pathways, these proteins promote the transition ... However, beyond PD-1/PD-L1 and CTLA-4, other immune checkpoints are emerging as important therapeutic targets.