CD8-overexpressing Jurkat cells against autologous organoids. We identified 5 novel tumor antigen-reactive TCRs that demonstrated tumor responsiveness and these T cells displayed a mixed ...

Research in the Marine Immunology Program focuses on basic and applied research on the health and immune systems of marine vertebrates, including cartilaginous fishes (sharks, skates, and rays), ...

As a loading control, mouse anti-GAPDH monoclonals (ab 9484, Abcam, Cambridge, United Kingdom) were used in 1:1,000 dilution, and as a positive control cell lysates from the Jurkat cell line ... using ...

Researchers at the University of Colorado Anschutz Medical Campus have successfully developed a supercharged iteration of CAR ...

Researchers have successfully developed a supercharged iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the cells, particularly against cancer cells that are harder ...

Scientists have supercharged CAR-T therapy, making it more powerful against elusive cancer cells that usually escape ...

It develops from the abnormal multiplication of T cells, or T-lymphocytes, a type of white blood cell essential for immune system function. The specific treatment course and prognosis for T-cell ...

Researchers at the University of Colorado Anschutz Medical Campus have successfully developed a supercharged iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the ...

A cancer therapy that uses genetically engineered immune cells, called CAR T-cells, has kept a person free of a potentially fatal nerve tumour for a record-breaking 18 years. “This is ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...