One of the world’s leading Parkinson’s disease scientists has warned of a potential pandemic of the neurological condition if ...

In a breakthrough for people living with Parkinson’s, a new study has finally determined the structure of a protein linked to ...

The team show PINK1 proteins attached to the membrane of a mitochondrion for the first time. Image: WEHI Dr Callegari says PINK1 works in four distinct steps, including sensing mitochondrial damage.

This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

WEHI researchers have made a huge leap forward in the fight against Parkinson's disease, solving a decades-long mystery that ...

WEHI researchers have made a huge leap forward in the fight against Parkinson’s disease, solving a decades-long mystery that paves the way for development of new drugs to treat the condition ...

New research provides key insights into the structure and function of PINK1, a protein linked to Parkinson's disease.

Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...