A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

CART, a next-gen CAR-T therapy for improved targeting and functionality to address this. “ALA-CART improves the ability of ...

With nearly 1.5 million people suffering from rheumatoid and juvenile arthritis in the United States, researchers at Shriners Children's St. Louis have discovered a revolutionary way to potentially ...

Decades later, HeLa cells were used in research for the COVID-19 vaccines, though there aren’t many details on the role they played. Cancer. In 1985, scientists used HeLa cells to find out ...

Precigen's PRGN-2012 and UltraCAR-Ts offer groundbreaking therapies. Read why PGEN stock is a strong pick, with major breakthroughs in RRP and cancer treatments.

some will continue to grow in the bone marrow and become B cells. Other lymphocytes will finish growing in the thymus and become T cells. B and T cells are the 2 major groups of lymphocytes that ...

CD8+ T cells accumulate in atherosclerotic plaques. Researchers identify a crucial signaling pathway -- with therapeutic potential.

As a loading control, mouse anti-GAPDH monoclonals (ab 9484, Abcam, Cambridge, United Kingdom) were used in 1:1,000 dilution, and as a positive control cell lysates from the Jurkat cell line ... using ...

CD8-overexpressing Jurkat cells against autologous organoids. We identified 5 novel tumor antigen-reactive TCRs that demonstrated tumor responsiveness and these T cells displayed a mixed ...

Rapid clonal expansion of antigen-specific T cells is a fundamental feature of adaptive immune responses. Here, we utilize continuous live-cell imaging in vitro to track the division speed and ...